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Essential thrombocytosis (0)

Essential thrombocytosis (primary thrombocythemia), first described by Epstein and Goedel in 1934, is a nonreactive, chronic myeloproliferative disorder.1 Essential thrombocytosis (primary thrombocythemia) is associated with sustained megakaryocyte proliferation that increases the number of circulating platelets. Traditionally, essential thrombocytosis (primary thrombocythemia) was considered a clonal disorder that involved pluripotent stem cells; however, studies have indicated that some patients may have polyclonal hematopoiesis.Essential thrombocytosis (primary thrombocythemia) is characterized by a platelet count greater than 600,000/µL, megakaryocytic hyperplasia, splenomegaly, and a clinical course complicated by thrombotic and/or hemorrhagic episodes.